Tirzepatide and semaglutide are GLP-1 (Glucagon-like peptide-1) receptor agonists, which means they mimic the action of a hormone called GLP-1 that helps regulate blood sugar and appetite. Tirzepatide is also a GIP (Glucose-dependent insulinotropic peptide) agonist, which promotes insulin release, and can help manage blood sugar levels. By slowing down gastric emptying and increasing feelings of fullness, these medications can help reduce overall food intake.
The combination of reduced appetite and better blood sugar control can lead to weight loss over time. However, these medications are most effective when combined with a healthy diet and regular physical activity.